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1.
Braz. J. Pharm. Sci. (Online) ; 58: e20117, 2022. tab, graf
Article in English | LILACS | ID: biblio-1403752

ABSTRACT

Abstract Population aging is a worldwide occurrence that has become urgent in developing countries. Quality of life can be measured to identify functional capacity and determine the degree of impact on quality of life exerted on an individual. This study aimed to measure the quality of life of elderly people who have been living in different long-term care facilities for the elderly. Therefore, this research was developed with a qualitative and descriptive approach. Data were obtained from medical records and interviews, and were analyzed in R language interpreter software on the Ubuntu Linux operating system. Seventy-nine elderly people participated in the study. Eleven lived in Home Marista, and 68 lived in Home Jesus Maria José. A socioeconomic questionnaire was used to collect data on the socioeconomic characteristics of the participants. The Mini-Mental State Exam was used to measure degree of cognition. The Short Form-36 Questionnaire was used to measure quality of life. The present study suggests that the results found can clarify the individual vulnerability of the elderly in the age group studied regardless of the type of residence. Despite the discrepancy found regarding the care provided at the long-term care facilities, the scores, obtained with the quality of life assessment, did not show significant differences.


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Quality of Life , Aged , Homes for the Aged/classification , Aging/genetics , Surveys and Questionnaires , Mental Status and Dementia Tests/standards
2.
Arq. neuropsiquiatr ; 77(11): 775-781, Nov. 2019. tab
Article in English | LILACS | ID: biblio-1055190

ABSTRACT

ABSTRACT The Montreal Cognitive Assessment (MoCA) has been described as a good tool to detect cognitive impairment. The ideal MoCA cutoff score is still under debate. The aim was to provide MoCA norms and accuracy data for seniors with a lower education level, including illiterates. Methods: Data originated from an epidemiological study conducted in the municipality of Tremembe, Brazil. The Brazilian MoCA test was applied as part of the cognitive assessment in all participants. Of the 630 participants, 385 were classified as cognitively normal (CN) and were included in the normative data set, 110 individuals were diagnosed with dementia and 135 were classified as having cognitive impairment no dementia (CIND). Results: The total scores varied significantly according to age and education among the three diagnostic groups: CN, CIND and dementia (p < 0.001). To distinguish participants with CN from dementia, the best MoCA cutoff was 15 points (sensitivity 90%, specificity 77%) and to differentiate those with CN from CIND, the MoCA cutoff was 19 points (sensitivity 84%, specificity 49%). Those scores varied according to education level. Conclusions: The MoCA test did not have a high accuracy for detecting CIND in the population with a low educational level. Nevertheless, this tool may be used to detect dementia, especially in individuals with more than five years of education, if a lower cutoff score is adopted.


RESUMO O Montreal Cognitive Assessment (MoCA) foi descrito como uma boa ferramenta para detectar comprometimento cognitivo. A nota de corte ideal do MoCA ainda está em debate. O objetivo é fornecer normas do MoCA e dados de acurácia para idosos dentro de uma faixa educacional mais baixa, incluindo analfabetos. Métodos: Os dados foram provenientes do estudo epidemiológico realizado no município de Tremembé, Brasil. A versão brasileira do MoCA foi aplicada como parte da avaliação cognitiva em todos os participantes. Dos 630 participantes, 385 foram classificados como cognitivamente normais (CN) e foram incluídos no conjunto de dados normativos, 110 indivíduos foram diagnosticados com demência e 135 foram classificados como tendo comprometimento cognitivo sem demência (CCSD). Resultados: Os escores totais variaram significativamente de acordo com a idade e escolaridade entre os três grupos diagnósticos: CN, CCSD e demência (p < 0,001). Para distinguir CN de demência, a melhor nota de corte do MoCA foi de 15 pontos (sensibilidade 90%, especificidade 77%) e para diferenciar o grupo CN de CCSD, a nota de corte do MoCA foi de 19 pontos (sensibilidade 84%, especificidade 49%). Essas notas de corte variaram conforme o nível de escolaridade. Conclusões: O teste MoCA não teve alta acurácia para detectar CCSD nesta população de baixa escolaridade. No entanto, esta ferramenta poderia ser usada para detectar demência, especialmente em indivíduos com mais de 5 anos de escolaridade, se uma menor nota de corte fosse adotada.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Dementia/diagnosis , Educational Status , Cognitive Dysfunction/diagnosis , Mental Status and Dementia Tests/standards , Psychiatric Status Rating Scales/standards , Reference Values , Brazil , Sex Factors , Cross-Sectional Studies , Reproducibility of Results , Analysis of Variance , Sensitivity and Specificity , Age Factors , Data Accuracy
3.
Rev. bras. neurol ; 54(4): 5-11, out.-dez. 2018. tab
Article in Portuguese | LILACS | ID: biblio-967818

ABSTRACT

OBJETIVO: A distrofia muscular de Duchenne (DMD) é frequentemente associada à deficiência intelectual (DI) e ao prejuízo de funções superiores como leitura, raciocínio, lógica, e memória. O objetivo do estudo foi avaliar o desempenho cognitivo de pacientes com DMD através do Mini-Exame do Estado Mental (MEEM), um teste simples e rápido, usado como primeiro rastreio intelectual, principalmente quando baterias psicométricas complexas, dependentes de psicólogos especializados, não estão disponíveis. MÉTODO: Foi realizado um estudo observacional de trinta e quatro meninos com DMD, com idades entre 8 e 22 anos, separados em dois grupos de acordo com a presença de DI moderada-grave, conforme a definição clínica do funcionamento adaptativo do Manual Estatístico e Diagnóstico de Desordens Mentais 5º edição (DSM-5). Foram avaliados a pontuação no MEEM, marcos do desenvolvimento, independência nas atividades de vida cotidiana e capacidade de alfabetização. RESULTADOS: Os marcos motores e de linguagem estavam atrasados (16 meses), e a média no MEEM foi 21, ponto de corte mais baixo do que verificado em pares da mesma idade. O grupo com DI moderada-grave apresentou uma média de 12 no MEEM, e os subtestes de orientação, atenção e cálculo e linguagem foram os que demonstraram piores desempenhos. O ponto de corte de maior acurácia para distinguir DI moderada-grave nos pacientes com DMD foi 21. CONCLUSÃO: O MEEM apresentou adequada sensibilidade (100%) e especificidade (90%) para o ponto de corte de 21, revelando-se um bom método de triagem cognitiva para DI moderada-grave na DMD.


BACKGROUND: Duchenne muscular dystrophy (DMD) is often associated with intellectual disability (ID) and with impairment of higher mental functions as reading, learning, logical thinking and memory. The goal of this study was evaluate the cognitive performance of DMD patients by Mini-Mental State Examination (MMSE), first bedside screening test, widely used in pediatrics, when neuropsychologic batteries, dependent on specialized psychologists, are not easily available in public health system. METHODS: An observational study of thirty-four boys with DMD, aged 8-22 years, was performed, spliting this group into two sub-groups, according to the presence of moderate-severe, defined by Diagnostic and Statistical Manual of Mental Disorders (DSM-5) adaptative functioning clinical criteria. The MMSE scores, developmental milestones, independence in daily life activities and literacy skills were evaluated. RESULTS: Motor and language milestones were reached with 16 months, later than usual and mean on MMSE was 21, lower than in healthy pairs. In assessment by groups, patients with moderate-severe intellectual disability presented a performance in total MMSE (12) and orientation, attention/calculation and language MMSE subtests lower than patients without ID. The most accurate cutoff value on MMSE to distinguish moderate-severe intellectual disability in DMD patients was 21. CONCLUSION: This study has shown adequate sensitivity and specificity of the MMSE for detection of moderate-severe intellectual disability, with almost 100% sensitivity and 90% specificity for cutoff values of 21 points in DMD.


Subject(s)
Humans , Male , Child , Adolescent , Muscular Dystrophy, Duchenne/complications , Muscular Dystrophy, Duchenne/diagnosis , Muscular Dystrophy, Duchenne/genetics , Intellectual Disability/diagnosis , Intellectual Disability/etiology , Cross-Sectional Studies , Sensitivity and Specificity , Observational Studies as Topic , Mental Status and Dementia Tests/standards
4.
São Paulo med. j ; 136(5): 390-397, Sept.-Oct. 2018. tab, graf
Article in English | LILACS | ID: biblio-979385

ABSTRACT

ABSTRACT BACKGROUND: Praxis impairment may be one of the first symptoms manifested in dementia, primarily in cortical dementia. The Cambridge Cognitive Examination (CAMCOG) evaluates praxis, but little is known about the accuracy of CAMCOG for diagnosing dementia. The aims here were to investigate the accuracy of praxis and its subitems in CAMCOG (constructive, ideomotor and ideational subitems) for diagnosing Alzheimer's disease (AD) among elderly patients. DESIGN AND SETTING: Cross-sectional study on community-dwelling elderly people. METHODS: 158 elderly patients were evaluated. CAMCOG, Mini-Mental State Examination and Pfeffer Functional Activities Questionnaire were used. ROC curve analysis was used to establish cutoff points. RESULTS: The total scores for praxis and the constructive subitem presented significant differences (P < 0.0001) between healthy elderly people and AD patients. Stage of dementia (clinical dementia rating, CDR = 0, 1 and 2) showed that total and constructive praxis can be used to classify the stages of dementia (mild and moderate cases), i.e. constructive praxis classified 88% of the patients with mild dementia (P < 0.0001) while total praxis classified 56% with moderate dementia. Comparison of normal controls (NC) and mild dementia cases showed specificity of 71% and sensitivity of 88% (AUC = 0.88; P < 0.0001). CONCLUSION: Some praxis subtests can have higher predictive diagnostic value for detecting Alzheimer's disease in mild stages (total praxis AUC = 0.858; P < 0.0001; constructive AUC = 0.972; P < 0.0001). Constructive praxis as measured using CAMCOG may contribute towards diagnosing dementia, because occurrence of impairment of praxis may help in recognizing an evolving dementia syndrome.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Alzheimer Disease/diagnosis , Mental Status and Dementia Tests/standards , Reference Values , Task Performance and Analysis , Case-Control Studies , Geriatric Assessment/methods , Cross-Sectional Studies , Reproducibility of Results , Sensitivity and Specificity , Cognition Disorders/diagnosis , Statistics, Nonparametric , Alzheimer Disease/physiopathology
5.
Rev. cuba. inform. méd ; 8(1)ene.-jun. 2016.
Article in Spanish | LILACS, CUMED | ID: lil-785007

ABSTRACT

La cantidad de personas que ascienden a la tercera edad aumentó en 700 millones en la década del 90, a nivel mundial. Para el año 2025 se estima que existirán cerca de 2 mil millones de ancianos. El cuidado de su salud reviste vital importancia para todas las sociedades; por ello, en el presente trabajo se propone una herramienta matemático computacional para medir la ejercitación de la atención y la percepción en el ambiente diario del adulto mayor. Ambas funciones poseen una estrecha relación con la capacidad psicológica de la memoria; además, se considera que su afectación puede provocar pérdida de validismo, dependencia y discapacidad, una vez que se ha iniciado el deterioro cognitivo. La propuesta es aplicada en la ciudad de Pinar del Río, Cuba a través de test experimentales y diferentes tipos de análisis mediante medios de cómputo en una muestra de personas de la tercera edad, con una capacidad moderadamente razonable(AU)


The number of old persons increased in 700 millions in the 90's at world level. This number will increase to nearly 2 thousand more million in 2025. The carefulness of their healthy becomes an important issue for all societies; that is why, in this research, it is presented a computational tool to measure the assistance and the perception in the daily environment of the elderly people. Both functions have a close relationship with the psychological capacity of the memory; moreover, it is considered that their damage can provoke loss of skills, dependence and disabilities, once the cognitive deterioration has begun. The proposal is applied in the pinar del río, cuba, through experimental tests and different types of analysis by means of computational in a sample of elderly people with a moderately reasonable capacity(AU)


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Medical Informatics Applications , Software Design , Aged/psychology , Cognition Disorders/psychology , Mental Status and Dementia Tests/standards , Cuba
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